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Do proton pump inhibitors decrease calcium absorption?

Published in Journal of Bone and Mineral Research • Nov 23, 2010
NobleIDNI4P22W36R44S88
Authors:
Karen E Hansen
,
Andrea N Jones
,
Mary J Lindstrom

Abstract

Abstract Proton pump inhibitors (PPIs) increase osteoporotic fracture risk presumably via hypochlorhydria and consequent reduced fractional calcium absorption (FCA). Existing studies provide conflicting information regarding the direct effects of PPIs on FCA. We evaluated the effect of PPI therapy o...

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