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Translating the Histone Code

Published in Science • Aug 10, 2001
NobleIDNI4P36W21R62S36
Authors:
Thomas Jenuwein
,
C. David Allis

Abstract

Chromatin, the physiological template of all eukaryotic genetic information, is subject to a diverse array of posttranslational modifications that largely impinge on histone amino termini, thereby regulating access to the underlying DNA. Distinct histone amino-terminal modifications can generate syn...

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