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Increasing plasma ketamine concentrations decrease the minimum alveolar concentration of isoflurane in rabbits.

Published in Frontiers in veterinary science • Jan 1, 2025
NobleIDNI0P60W42R58S50
Authors:
Linda S Barter
,
Bruno H Pypendop

Abstract

To evaluate the effects of increasing plasma ketamine concentration on isoflurane minimum alveolar concentration (MAC) in rabbits, six New Zealand white rabbits weighing 4.21 ± 0.35 kg were anesthetized with isoflurane in oxygen. Ketamine was given intravenously to target pseudo-steady-state plasma ...

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