BASE FLIPPING
Published in Annual Review of Biochemistry • Jun 1, 1998
Authors:,
Richard J. Roberts
Xiaodong Cheng
Abstract
Base flipping is the phenomenon whereby a base in normal B-DNA is swung completely out of the helix into an extrahelical position. It was discovered in 1994 when the first co-crystal structure was reported for a cytosine-5 DNA methyltransferase binding to DNA. Since then it has been shown to occur i...
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