Self‐assembled verteporfin nanoparticles decrease drug efflux by P‐glycoprotein without light activation in drug‐resistant cancer cells
Published in Bioengineering & Translational Medicine • Mar 20, 2026
NobleIDNI7P88W23R90S19
Authors:,,
Idrisa Rahman
Anju Meda
Kaitlyn A. Moore
Abstract
Abstract P‐glycoprotein (P‐gp)‐mediated multidrug resistance (MDR) remains one of the major obstacles to successful chemotherapy for cancer. Previous studies have shown that photodynamic therapy and priming using verteporfin (VP) decrease the drug efflux by P‐gp and improve chemotherapy efficacy. De...
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