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Self‐assembled verteporfin nanoparticles decrease drug efflux by P‐glycoprotein without light activation in drug‐resistant cancer cells

Published in Bioengineering & Translational Medicine • Mar 20, 2026
NobleIDNI7P88W23R90S19
Authors:
Idrisa Rahman
,
Anju Meda
,
Kaitlyn A. Moore

Abstract

Abstract P‐glycoprotein (P‐gp)‐mediated multidrug resistance (MDR) remains one of the major obstacles to successful chemotherapy for cancer. Previous studies have shown that photodynamic therapy and priming using verteporfin (VP) decrease the drug efflux by P‐gp and improve chemotherapy efficacy. De...

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