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Neurite beading is sufficient to decrease the apparent diffusion coefficient after ischemic stroke

Published in Proceedings of the National Academy of Sciences • Jul 26, 2010
NobleIDNI6P57W94R03S95
Authors:
Matthew D. Budde
,
Joseph A. Frank

Abstract

Diffusion-weighted MRI (DWI) is a sensitive and reliable marker of cerebral ischemia. Within minutes of an ischemic event in the brain, the microscopic motion of water molecules measured with DWI, termed the apparent diffusion coefficient (ADC), decreases within the infarcted region. However, althou...

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