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Decrease in Mitochondrial Complex I Activity in Ischemic/Reperfused Rat Heart

Published in Circulation Research • Jan 9, 2004
NobleIDNI9P05W38R70S79
Authors:
Giuseppe Paradies
,
Giuseppe Petrosillo
,
Marilva Pistolese

Abstract

Reactive oxygen species (ROS) are considered an important factor in ischemia/reperfusion injury to cardiac myocytes. Mitochondrial respiration is an important source of ROS production and hence a potential contributor to cardiac reperfusion injury. In this study, we have examined the effect of ische...

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