Depression
Published in An Introduction to Evolutionary Medicine • Dec 18, 2026
Authors:,
Alan D Penman
Joe Alcock
Abstract
The high prevalence of major depressive disorder, along with its lethality and morbidity, poses an evolutionary paradox. The underlying neural architecture of mood may have been adaptive in an ancestral environment, but it is maladaptive (mismatched) in a modern environment, with harm resulting from...
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