Intermittent low-efficiency hemodiafiltration causes a marked decrease in ampicillin and sulbactam plasma concentration in dogs with oliguric acute kidney injury
Published • Jan 1, 2026
Authors:,,
Amédée André
Bernadette Espana
Alexandra Nectoux
Abstract
Dogs with oliguric acute kidney injury (AKI) of infectious etiology are frequently managed with renal replacement therapy (RRT) and β-lactam antibiotics. Ampicillin and sulbactam are small, hydrophilic, renally eliminated molecules susceptible to extracorporeal clearance during RRT, yet the magnitud...
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