Escuela Superior Politécnica del Chimborazo

Willd.) is a genetically diverse Andean crop that has earned special attention worldwide due to its nutritional and health benefits and its ability to adapt to contrasting environments, including nutrient-poor and saline soils and drought stressed marginal agroecosystems. Drought and salinity are the abiotic stresses most studied in quinoa; however, studies of other important stress factors, such as heat, cold, heavy metals, and UV-B light irradiance, are severely limited. In the last few decades, the incidence of abiotic stress has been accentuated by the increase in unpredictable weather patterns. Furthermore, stresses habitually occur as combinations of two or more. The goals of this review are to: (1) provide an in-depth description of the existing knowledge of quinoa's tolerance to different abiotic stressors; (2) summarize quinoa's physiological responses to these stressors; and (3) describe novel advances in molecular tools that can aid our understanding of the mechanisms underlying quinoa's abiotic stress tolerance.

Fractionation of a methanolic extract of the leaves of Anthurium versicolor has resulted in the isolation of two main fractions, I and II. Both the extract and the fractions were assayed for their radical-scavenging activity by means of an in vitro test (bleaching of the stable 1,1-diphenyl-2-picrylhydrazyl radical) and showed a significant radical-scavenging effect. Subsequent chromatographic fractionation of the most active fraction, II, has led to the isolation and characterization, as major constituents, of four new flavone glycosides, acacetin 6-C-[alpha-L-rhamnopyranosyl-(1-->3)-beta-D-glucopyranoside] (1), acacetin 6-C-[beta-D-xylopyranosyl-(1-->6)-beta-D-glucopyranoside] (2), acacetin 6-C-[beta-D-apiofuranosyl-(1-->3)-beta-D-glucopyranoside] (3), and acacetin 8-C-[alpha-L-rhamnopyranosyl-(1-->3)-beta-D-glucopyranoside] (4), as well as vitexin (apigenin-8-C-beta-D-glucopyranoside) and rosmarinic acid. The structures of 1-4 were determined using spectroscopic methods.

Objective: This umbrella review aims to ascertain the extent to which immersive Virtual Reality (VR) and Augmented Reality (AR) technologies improve specific competencies in healthcare professionals within medical education and training, in contrast to traditional educational methods or no intervention. Methods: Adhering to PRISMA guidelines and the PICOS approach, a systematic literature search was conducted across major databases to identify studies examining the use of VR and AR in medical education. Eligible studies were screened and categorized based on the PICOS criteria. Descriptive statistics and chi-square tests were employed to analyze the data, supplemented by the Fisher test for small sample sizes or specific conditions. Analysis: The analysis involved cross-tabulating the stages of work (Development and Testing, Results, Evaluated) and variables of interest (Performance, Engagement, Performance and Engagement, Effectiveness, no evaluated) against the types of technologies used. Chi-square tests assessed the associations between these categorical variables. Results: = 0.052), suggested a non-significant trend toward the association of VR with improved outcomes. Conclusions: The results indicate that VR is a prevalent tool in the research landscape of medical education technologies, with a positive trend toward enhancing educational outcomes. However, the statistical analysis did not reveal a significant association, suggesting the need for further research with larger sample sizes. This review underscores the potential of immersive technologies to enhance medical training yet calls for more rigorous studies to establish definitive evidence of their efficacy.

Recently, green-prepared oxidized graphenes have attracted huge interest in water purification and wastewater treatment. Herein, reduced graphene oxide (rGO) was prepared by a scalable and eco-friendly method, and its potential use for the removal of methylene blue (MB) from water systems, was explored. The present work includes the green protocol to produce rGO and respective spectroscopical and morphological characterizations, as well as several kinetics, isotherms, and thermodynamic analyses to successfully demonstrate the adsorption of MB. The pseudo-second-order model was appropriated to describe the adsorption kinetics of MB onto rGO, suggesting an equilibrium time of 30 min. Otherwise, the Langmuir model was more suitable to describe the adsorption isotherms, indicating a maximum adsorption capacity of 121.95 mg g−1 at 298 K. In addition, kinetics and thermodynamic analyses demonstrated that the adsorption of MB onto rGO can be treated as a mixed physisorption–chemisorption process described by H-bonding, electrostatic, and π − π interactions. These results show the potential of green-prepared rGO to remove cationic dyes from wastewater systems.

Fractionation of a methanol extract of the leaves and twigs of Casearia sylvestris, as directed by activity against KB cell cytotoxicity, led to the isolation of three novel clerodane diterpenoids, casearvestrins A-C (1-3). The structures of 1-3 were deduced from one- and two-dimensional NMR experiments, including relative stereochemical assignments based on ROESY correlations and COSY coupling constants. All three compounds displayed promising bioactivity, both in cytotoxicity assays against a panel of tumor cell lines and in antifungal assays via the growth inhibition of Aspergillus niger in a disk diffusion assay.

The oxidative exfoliation of graphite is a promising approach to the large-scale production of graphene. Conventional oxidation of graphite essentially facilitates the exfoliation process; however, the oxidation procedure releases toxic gases and requires extensive, time-consuming steps of washing and reduction to convert exfoliated graphene oxide (GO) into reduced graphene oxide (rGO). Although toxic gases can be controlled by modifying chemical reactions, filtration, dialysis, and extensive sonication are unfavorable for large-scale production. Here, we report a complete, scalable, and green synthesis of GO, without NaNO3, followed by reduction with citric acid (CA). This approach eliminates the generation of toxic gases, simplifies the washing steps, and reduces the time required to prepare rGO. To validate the proposed method, we present spectroscopical and morphological studies, using energy-dispersive X-ray spectroscopy (EDS), UV-visible spectroscopy, infrared spectroscopy, Raman spectroscopy, scanning electron microscopy (SEM), and transmission electron microscopy (TEM). Thermal gravimetric analysis (TGA) is used to analyze the thermal properties of GO and rGO. This eco-friendly method proposes a complete guideline protocol toward large-scale production of oxidized graphene, with potential applications in supercapacitors, fuel cells, composites, batteries, and biosensors.

Medicinal plants are an ecosystem service directly implicated in human well-being. In many rural communities, they constitute a main treatment for disease or a source of disease prevention. Here, we review traditional knowledge of medicinal plants, the benefits they provide when cultivated in home gardens, and the determinants of knowledge about their uses in a rural parish in Amazonian Ecuador, where two ethnic groups prevail: indigenous Shuar and settled mestizos. Among 138 garden owners interviewed in 11 communities, a broad knowledge of 104 pharmacological properties across 145 medicinal plant species is retained. Several species play a specific role for a particular culture; therefore, the importance ranking of medicinal plants is different between the two main cultures. Traditional knowledge of medicinal uses is also influenced by ethnicity as well as generational age of the gardeners. Knowledge seems to have been lost in people of younger generations, who cultivated fewer species and knew less about properties of medicinal plants. Although men cultivate more diverse gardens, the role for women in the conservation of agrobiodiversity in home gardens appears crucial, as they are identified as the main source for transmission of traditional knowledge about medicinal plants. Our study highlights the importance of integrated land use management that respects different social aspects (i.e., culture, gender, health and well-being) related to conservation of biodiversity and traditional knowledge in agroecosystems.

Island ecosystems have very specific physical, economic and socio-cultural characteristics, which are shared by most of these ecosystems regardless of their geographical area. These characteristics include well defined geographical boundaries that lead to a greater degree of isolation, lack of economically exploitable resources, great external dependence for consumption, cultural and natural heritage with a high uniqueness level and a high concentration of endemic plant and animal species. All of them are responsible for the high development dependence level linked to the tourism activity of these ecosystems. Thus, island ecosystems are currently an important international tourism destination, where a great diversity of very attractive natural and cultural resources and of great heritage value are concentrated. This fact allows for the development of tourism activities of great heterogeneity among countries or regions of the world that host these island ecosystems. The aim of this research was to identify and analyze, through a bibliometric and bibliographic analysis, the scientific production indexed in the international Scopus database, which addresses the subject of use of cultural and natural resources by tourism in island ecosystems. This scientific mapping allows us to observe the evolution of scientific production in this field of study. The results show that this is a new subject (a large number of transient authors), predominantly affiliated with the United States and Spain. The most followed research lines to date are destination management followed very far by responsible environmental behavior and the impacts of sustainable development. However, the keywords with the highest co-occurrence show that the hot topics are tourism exploitation in the ecotourism field and sustainable tourism development. This research is considered the first bibliometric study carried out which is related to this thematic approach, providing a clear in-depth analysis for researchers and thereby facilitating the approach of future research work.

Abstract Transnational textile companies claim to have put in a place processes of corporate social responsibility to promote ethical behaviour in regard to the economy, environment, and populations within which they operate. However, their true conduct, behind the mask of marketing campaigns, may be better defined as corporate social irresponsibility. The objective of this study was to analyze and explore the processes of CSiR within the textile sector as being the rule and not the exception. A broad review of the available literature was carried out, both as a literal and conceptual analysis, covering 133 approaches to the hitherto undefined concept of CSiR. In addition, a Google frequency count was performed, with a saturated categorization using the five dimensions into which the CSiR processes are concentrated: ethical, legal, social, economic, and environmental. The methodology used was based on a higher order association of these hierarchies, for which a triad model was established, allowing the most representative combinations to be identified. This methodology demonstrated that the environmental dimension is of residual character, while allowing the definitions of greater weight and scope to be extracted. From these, it was inferred that the current concept of CSiR is best defined in a three‐fold legal‐social‐ethical category, based on its frequency of use in Google, its effective application, and scope. The definition provided by this study may contribute to the improvement of the ethical processes of entrepreneurship and CSR by highlighting their taxonomy of inconsistencies, rather than focusing on the preconceived benefits of their actions.

El presente artículo manifiesta la importante concepción y uso de las tecnologías de la información como herramientas que han permitido desarrollar el proceso de enseñanza aprendizaje en la educación, facilitando tanto al docente como al alumnado la adquisición del conocimiento de forma más inmediata y amplia; el gran impacto del desarrollo tecnológico que se está originando en la actualidad ha favorecido lo que se denomina la nueva revolución social, las TIC han generado grandiosos cambios en las organizaciones culturales, sociales, económicas y educativas. Estas manifiestan una serie de características fundamentales como una vía factible a todo tipo de información, establece una comunicación inmediata, ya sea sincrónica o asincrónica, en la automatización de las actividades, almacenamiento de numerosa información y la interacción entre computadores y usuarios. El docente cumple un rol fundamental en el conocimiento y uso de estas tecnologías, debido a la importancia didáctica que pueden tener las TIC empleadas adecuadamente en el aula de clase. Sin embargo, los docentes hoy en día no comprenden con eficacia la utilidad que puede significar el uso de las TIC en el desarrollo del proceso de formación de los estudiantes; esto se refleja en la calidad educativa. Por lo cual este manuscrito tiene como objetivo analizar Las Tecnologías de la Información y la Comunicación como forma investigativa interdisciplinaria con un enfoque intercultural para fortalecer el proceso de formación de los estudiantes.

Methods are needed for helping researchers and farmers to interactively describe and analyze local practices in search of opportunities for improving health, environment, and economy. The authors worked with smallholder family farmers in five Andean villages in Ecuador to apply participatory four-cell analysis (PFCA) in characterizing agrobiodiversity. Margelef and Shannon indices examined ecological richness and evenness, and a simplified 24-hour dietary recall characterized food consumption. Cross-analysis tested interactions among agrobiodiversity, farm size, and diet. Overall trends appeared to work against sustainable intensification, with notable heterogeneity and positive deviance found in the practices of relatively smaller enterprises, representing a potential resource for sustainable intensification. The suite of methods was determined useful for initiating researcher-farmer explorations of promising innovation pathways.

This study focused on the study of the changes originated in the milk from partum until d 90 of lactation. Ten multiparous Majorera goats, bred carefully under animal health standards, with a litter size of 2 kids (the average in this breed is 1.83 prolificacy) and similar gestation length (149 ± 1 d) were used. Goat kids were removed from their dams to avoid interferences with the study. Compositional content (fat, protein, and lactose) were measured, as well as some other properties, including pH, density, titratable acidity, ethanol stability, rennet clotting time, and somatic cell count. Moreover, immunity molecules (IgG, IgA, and IgM concentrations and chitotriosidase activity) received great attention. Fat and protein content were higher in the first days postpartum, whereas lactose content was lower. Density, titratable acidity, rennet clotting time, and somatic cell count decreased throughout the lactation period, whereas pH and ethanol stability increased. Relative to the immunological parameters, each measured parameter obtained its maximum level at d 0, showing the first milking as the choice to provide immunity to the newborn kids. On the other hand, this study might be used to establish what the best use is: processing or kid feeding.

La década de los 70 en que inicia la revolución electrónica constituyó el punto de partida para el desarrollo creciente de la era digital. Los rápidos avances tecnológicos han permitido que las Tecnologías de Información y Comunicación se implementen dentro de los procesos educativos a través del uso de redes sociales y elementos multimedia. El estudio de las investigaciones referentes a la creación de cuestionarios utilizados para medir el conocimiento, uso y gestión de estas tecnologías en la educación universitaria presentan varios inconvenientes como el desmedido número de preguntas que los vuelve extensos además se plantea un contexto abierto que impide definir resultados centrados en aspectos específicos. El presente trabajo científico obtuvo como resultado un cuestionario rediseñado y sometido a un análisis de fiabilidad, obteniéndose un ALFA DE CRONBACH de 0.905, considerando que tiene un excelente nivel de fiabilidad, y está enfocado en medir aspectos como el conocimiento, uso y actitud que los docentes presentan frente a la implementación de la tecnología en el proceso de enseñanza aprendizaje de las clases presenciales.

Artisanal and small-scale gold mining (ASGM) and large-scale mining in the Ecuadorian Amazon region is potentially harmful to nature, and its impacts are associated with environmental degradation and deterioration of people’s health. So far, limited efforts have been directed at exploring the current situation and challenges facing the implementation of environmental policies in the country. The objective of this study focused on analyzing the historical and current situation and challenges of ASGM in the Amazon region of Ecuador in relation to a political perspective (laws), socioeconomic impacts (population displacement, loss of livelihoods, migration of people, cost of living, water scarcity, and health impacts), and environmental impacts (biotic and abiotic). The methodology used was based on a literature review and interviews, and information that was discussed through an expert judgment allowed for establishing challenges to improve ASGM management. The main results indicate that lack of community participation in decision-making, insufficient coordination between government institutions, communities, and miners, and lack of control of mining activities are factors that contribute to ineffective compliance with environmental policies in the gold mining sector in the Amazon. Finally, the study concludes by considering the socioeconomic and environmental scopes within its findings for implementing effective environmental and social policies in the Amazon region of Ecuador.

Biodiversity is vital for the stability of the planet; its ecosystem services provide essential elements for our survival and well-being. This review analyzes the national biodiversity policies and describes the main strategies for biodiversity conservation in Ecuador, one of the “mega-diverse” countries in the world with the highest species density. It deepens an analysis of in-situ and ex-situ conservation processes. Ecuador has six clear policies for biodiversity conservation. These policies strengthen biodiversity conservation through mechanisms that improve the well-being of wildlife by ensuring human, wildlife and ecosystem health. It promotes actions for the welfare of wildlife, through technical, administrative and legal tools. The National System of Protected Areas, with 60 protected areas, is the most effective in-situ conservation instrument at the country level. Several ex-situ conservation and management means for the conservation of wild species are being utilized, including nurseries, botanical gardens, zoos, germplasm banks, aquariums, species reproduction and rehabilitation centers. Ecuador is making slow progress on ex-situ conservation despite the availability of a sound policy framework, possibly due to financial, infrastructural, and/or technological challenges, and knowledge gaps. We propose fostering international research collaborations and establishing fully funded small-scale captive breeding programs at zoos, aquariums and university research facilities to help recovery of at-risk species of reptiles, amphibians, fish and species beyond Galapagos region. We recommend utilizing citizen science programs to fill the gaps of biodiversity information and increasing efforts to revive the ex-situ conservation strategies in protecting the unique biodiversity of Ecuador.

Entrepreneurship and social innovation nowadays have an important role in the economic and social development of countries, and this is corroborated because the highest levels of development correspond to those nations that reveal the highest levels of innovative entrepreneur ship in their countries. Economies in recent years there has been great interest in innovation and its impact on companies, however, social innovation has to do with new social practices created to help people. With the development of technologies, new companies have emerged and with-it new forms of communication have been created, more needs, in addition to the creation of new jobs directly and indirectly, which activates the economy and improves the quality of life of the people. When talking about entrepreneurship we refer to innovation and how this helps to make a difference between similar products and services. The objective of the article is to investigate innovation and entrepreneurship and its impact on economic and social development for which a systematic review of the bibliography of entrepreneurship and social innovation was carried out, focusing on knowing the impacts that it generates, through Inventions and helping people. It can be concluded that it is clear that innovation and entrepreneurship are some of the key elements in the development of companies and their impacts benefit society in general.

Currently, the management of urban waste streams in developing countries is not optimized yet, and in many cases these wastes are disposed untreated in open dumps. This fact causes serious environmental and health problems due to the presence of contaminants and pathogens. Frequently, the use of specific low-cost strategies reduces the total amount of wastes. These strategies are mainly associated to the identification, separate collection and composting of specific organic waste streams, such as vegetable and fruit refuses from food markets and urban gardening activities. Concretely, in the Chimborazo Region (Ecuador), more than 80% of municipal solid waste is dumped into environment due to the lack of an efficient waste management strategy. Therefore, the aim of this study was to develop a demonstration project at field scale in this region to evaluate the feasibility of implanting the composting technology not only for the management of the organic waste fluxes from food market and gardening activities to be scaled-up in other developing regions, but also to obtain an end-product with a commercial value as organic fertilizer. Three co-composting mixtures were prepared using market wastes mixed with pruning of trees and ornamental palms as bulking agents. Two piles were created using different proportions of market waste and prunings of trees and ornamental palms: pile 1 (50:33:17) with a C/N ratio 25; pile 2: (60:30:10) with C/N ratio 24 and pile 3 (75:0:25) with C/N ratio 33), prepared with market waste and prunings of ornamental palm. Throughout the process, the temperature of the mixtures was monitored and organic matter evolution was determined using thermogravimetric and chemical techniques. Additionally, physico-chemical, chemical and agronomic parameters were determined to evaluate compost quality. The results obtained indicated that all the piles showed a suitable development of the composting process, with a significant organic matter decomposition, reached in a shorter period of time in pile 3. At the end of the process, all the composts showed absence of phytotoxicity and suitable agronomic properties for their use as organic fertilizers. This reflects the viability of the proposed alternative to be scaled-up in developing areas, not only to manage and recycle urban waste fluxes, but also to obtain organic fertilizers, including added value in economic terms related to nutrient contents.

Objective This systematic review aims to synthesize current knowledge on integrating immersive technologies, namely Virtual Reality (VR) and Augmented Reality (AR), in Science, Technology, Engineering, Mathematics (STEM) education, and to lighten their impact on student performance and engagement. Methods Adhering to PRISMA guidelines, a detailed search strategy across Scopus and Web of Science databases identified relevant peer-reviewed journal articles published from 2002 to 2023. The PICOS approach informed our inclusion criteria, focusing on empirical studies that assessed the application of VR and AR technologies in Science, Technology, Engineering, Mathematics (STEM) educational settings. Studies were evaluated for methodological quality, and data extraction was meticulous, with variables categorized as engagement, performance, or a combination of both. Analysis A descriptive and statistical analysis using chi-square tests was employed to examine the relationship between the type of technology (AR, VR, XR, MR) and the educational outcomes. This quantitative assessment provided a nuanced understanding of the interplay between various immersive technologies and their pedagogical effectiveness. Results Out of 143 initially identified articles, 22 met the inclusion criteria for detailed analysis. Findings revealed that AR was the most studied technology, followed by VR. Most studies reported positive effects on student engagement and performance, with increased effectiveness being less frequently observed. A notable portion of the studies specifically investigated the combination of performance and engagement, underscoring the multifaceted benefits of immersive technologies in education. Conclusions Immersive technologies are reshaping STEM education by enhancing engagement and performance. Integrating VR and AR offers promising educational benefits, including improved comprehension of complex concepts, increased student motivation, and enriched collaborative learning experiences. However, the field requires a globally inclusive and adaptable framework for rapid technological evolution and diverse educational contexts. Future research should broaden its scope to include multilingual literature and non-traditional academic channels, ensure ethical standards are upheld, and focus on personalization and adaptability to maximize the educational potential of these technologies.

Several factors can affect lamb body weight (BW) and immune status during the first days of life, including colostrum source and timing of the first colostrum feeding. The aim of this study was to evaluate the effects of colostrum source (goat or sheep) and timing of the first colostrum feeding (2 or 14h after birth) on lamb BW and immune status. In this study, 40 lambs were removed from their dams at birth and randomly assigned into 4 groups of 10 lambs each. Lambs were subsequently fed at 2 or 14h after birth with goat or sheep colostrum. Blood samples and BW recording were performed before feeding. Blood plasma was used to measure the immunoglobulin concentration (IgG and IgM), chitotriosidase activity, and complement system activity (total and alternative pathways). In general, no differences in any of the measured variables were observed among the 4 groups, indicating that neither colostrum source nor timing of the first colostrum feeding had an effect on these variables. These findings may improve management on lamb farms that raise animals under artificial conditions, because our results indicate that it is not necessary to feed colostrum to lambs immediately after birth and that goat colostrum may be used to feed newborn lambs.

In recent years, n-butanol produced from waste or lignocellulosic materials has become an attractive and sustainable green energy source for diesel engines because has a clear potential for the partial substitution of fossil-based diesel fuel. This study aims to analyse the effects of different n-butanol/diesel fuel blends on the performance and exhaust emissions of a Euro V heavy-duty diesel engine following the World Harmonised Steady-State Cycle (WHSC), as well as the effect of each mode on the test averaged results. The blends evaluated here were blends of conventional diesel fuel with 5%, 10% and 20% (by volume) n-butanol. Conventional diesel fuel was used as a reference fuel to compare the performance and emission characteristics of the different n-butanol blends. The main findings show that 10% butanol could be considered as a suitable proportion for blending n-butanol/conventional diesel owing to its favourable performance and reduction in particulate emissions, without significant changes in the gaseous emissions of NOX. Mode-by-mode comparative analysis results show improved engine performance with the use of n-butanol in most modes, regardless of speed or load conditions. CO emissions in general increase, despite the incorporation of n-butanol reduces CO emissions under high-load and low-speed conditions. THC emissions increase with n-butanol, being more critical under cold start conditions. The influence of n-butanol on NOX emissions does not have a clear trend, but it is observed that NO2 emissions decrease in all modes with the use of n-butanol blends, mainly in low load modes.