Endothelial NLRP3 inflammasome activation and enhanced neointima formation in mice by adipokine visfatin.

Inflammasomes serve as an intracellular machinery to initiate inflammatory response to various danger signals. The present study tested whether an inflammasome centered on nucleotide oligomerization domain-like receptor protein 3 (NLRP3) triggers endothelial inflammatory response to adipokine visfat... View More