Delayed treatment with 1,3-butanediol reduces loss of CA1 neurons in the hippocampus of rats following brief forebrain ischemia.

NR, Sims; SL, Heward

doi:10.1016/0006-8993(94)90815-x

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Delayed treatment with 1,3-butanediol reduces loss of CA1 neurons in the hippocampus of rats following brief forebrain ischemia.

Shared by NobleBlocks on Oct 1, 1994 • 12:00 AM UTC

Authors:

Sims NR

Heward SL

Abstract

This study examined the effect of 1,3-butanediol on the selective loss of CA1 pyramidal neurons following a short period of near-complete forebrain ischemia. Injection of 55 mmol 1,3-butanediol/kg body weight at 24 h of recirculation and again at 36 h following 10 min of forebrain ischemia markedly ...

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