In Vitro Drug Sensitivity Testing Can Predict Induction Failure and Early Relapse of Childhood Acute Lymphoblastic Leukemia

Hongo, Teruaki; Yajima, Shuhei; Sakurai, Minoru; Horikoshi, Yasuo; Hanada, Ryoji

doi:10.1182/blood.v89.8.2959

Public

In Vitro Drug Sensitivity Testing Can Predict Induction Failure and Early Relapse of Childhood Acute Lymphoblastic Leukemia

Shared by NobleBlocks on Apr 15, 1997 • 12:00 AM UTC

Authors:

Teruaki Hongo

Shuhei Yajima

Minoru Sakurai

Abstract

It is vital to develop effective therapy for children with acute lymphoblastic leukemia (ALL), in whom no remission occurs or who suffer relapse with current protocols. Cellular drug resistance is thought to be an important cause of induction failure and relapse. We performed in vitro tests of bone ...

Subject

Medicine

Vincristine

Dexamethasone

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