Expression of programmed cell death ligand 1 is associated with poor overall survival in patients with diffuse large B-cell lymphoma.

J, Kiyasu; H, Miyoshi; A, Hirata; F, Arakawa; A, Ichikawa; D, Niino; Y, Sugita; Y, Yufu; I, Choi; Y, Abe; N, Uike; K, Nagafuji; T, Okamura; K, Akashi; R, Takayanagi; M, Shiratsuchi; K, Ohshima

doi:10.1182/blood-2015-02-629600

Public

Expression of programmed cell death ligand 1 is associated with poor overall survival in patients with diffuse large B-cell lymphoma.

Shared by NobleBlocks on Aug 3, 2015 • 12:00 AM UTC

Authors:

Kiyasu J

Miyoshi H

Hirata A

Abstract

Programmed cell death ligand 1 (PD-L1) is expressed on both select diffuse large B-cell lymphoma (DLBCL) tumor cells and on tumor-infiltrating nonmalignant cells. The programmed cell death 1 (PD-1)/PD-L1 pathway inhibits host antitumor responses; however, little is known about how this pathway funct...

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