Subcutaneous Low-Molecular Weight Heparin or Oral Anticoagulants for the Prevention of Deep-Vein Thrombosis in Elective Hip and Knee Replacement?

Patients who undergo major orthopaedic operations have a high risk of venous thromboembolism. Once daily fixed-dose subcutaneous nadroparine is at least as efficacious and safe as daily adjusted OAC for prophylaxis against DVT after hip or knee implantation but is more simple to administer.