Large‐scale essential gene identification in <i>Candida albicans</i> and applications to antifungal drug discovery

Roemer, Terry; Jiang, Bo; Davison, John; Ketela, Troy; Veillette, Karynn; Breton, Anouk; Tandia, Fatou; Linteau, Annie; Sillaots, Susan; Marta, Catarina; Martel, Nick; Veronneau, Steeve; Lemieux, Sebastien; Kauffman, Sarah; Becker, Jeff; Storms, Reginald; Boone, Charles; Bussey, Howard

doi:10.1046/j.1365-2958.2003.03697.x

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Large‐scale essential gene identification in <i>Candida albicans</i> and applications to antifungal drug discovery

Shared by NobleBlocks on Aug 27, 2003 • 12:00 AM UTC

Authors:

Terry Roemer

Bo Jiang

John Davison

Abstract

Summary Candida albicans is the primary fungal pathogen of humans. Despite the need for novel drugs to combat fungal infections [Sobel, J.D. (2000) Clin Infectious Dis 30: 652], antifungal drug discovery is currently limited by both the availability of suitable drug targets and assays to screen corr...

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