IL-28 elicits antitumor responses against murine fibrosarcoma.

M, Numasaki; M, Tagawa; F, Iwata; T, Suzuki; A, Nakamura; M, Okada; Y, Iwakura; S, Aiba; M, Yamaya

doi:10.4049/jimmunol.178.8.5086

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IL-28 elicits antitumor responses against murine fibrosarcoma.

Shared by NobleBlocks on Apr 1, 2007 • 12:00 AM UTC

Authors:

Numasaki M

Tagawa M

Iwata F

Abstract

IL-28 is a recently described antiviral cytokine. In this study, we investigated the biological effects of IL-28 on tumor growth to evaluate its antitumor activity. IL-28 or retroviral transduction of the IL-28 gene into MCA205 cells did not affect in vitro growth, whereas in vivo growth of MCA205IL...

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