Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction.

Hirata, Ken‐ichi; Kikuchi, Akira; Sasaki, Takuya; Kuroda, Shinya; Kaibuchi, Kozo; Matsuura, Yoshiharu; Seki, Hanae; Saida, K; Takai, Yoshimi

doi:10.1016/s0021-9258(19)50337-4

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Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction.

Shared by NobleBlocks on May 1, 1992 • 12:00 AM UTC

Authors:

Ken‐ichi Hirata

Akira Kikuchi

Takuya Sasaki

Abstract

In the rabbit mesenteric arterial smooth muscle skinned by saponin, Ca2+ induced contraction in a concentration-dependent manner. Guanosine 5'-(3-O-thio)triphosphate (GTP gamma S), a non-hydrolyzable GTP analogue, lowered the Ca2+ concentrations required for this contraction and increased the Ca2+ s...

Subject

Calcium

Contraction (grammar)

Biophysics

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