Coexistence of HER2 over-expression and p53 protein accumulation is a strong prognostic molecular marker in breast cancer.

Yamashita, Hiroko; Nishio, Mariko; Toyama, Tatsuya; Sugiura, Hiroshi; Zhang, Zhenhuan; Kobayashi, Shunzo; Iwase, Hirotaka

doi:10.1186/bcr738

Public

Coexistence of HER2 over-expression and p53 protein accumulation is a strong prognostic molecular marker in breast cancer.

Shared by NobleBlocks on Jan 1, 2004 • 12:00 AM UTC

Authors:

Hiroko Yamashita

Mariko Nishio

Tatsuya Toyama

Abstract

INTRODUCTION: Many laboratories are currently evaluating the usefulness of determination of HER2, p53, and Ki67 proliferation indices using immunohistochemical techniques in cancer. Although the available studies suggest that these factors might indeed be helpful in making treatment decisions in can...

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