Glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons.

P Gilman, Charles; Perry, TracyAnn; Furukawa, Katsotoshi; H Grieg, Nigel; M Egan, Josephine; P Mattson, Mark

doi:10.1046/j.1471-4159.2003.02073.x

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Glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons.

Shared by NobleBlocks on Dec 1, 2003 • 12:00 AM UTC

Authors:

Charles P Gilman

TracyAnn Perry

Katsotoshi Furukawa

Abstract

Glucagon-like peptide 1 (GLP-1) activates receptors coupled to cAMP production and calcium influx in pancreatic cells, resulting in enhanced glucose sensitivity and insulin secretion. Despite evidence that the GLP-1 receptor is present and active in neurons, little is known of the roles of GLP-1 in ...

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