A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

J. Vlahos, Chris; F. Matter, William; Y. Hui, K.; F. Brown, Raymond

doi:10.1016/s0021-9258(17)37680-9

Public

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

Shared by NobleBlocks on Feb 1, 1994 • 12:00 AM UTC

Authors:

Chris J. Vlahos

William F. Matter

K. Y. Hui

Abstract

Phosphatidylinositol (PtdIns) 3-kinase is an enzyme implicated in growth factor signal transduction by associating with receptor and nonreceptor tyrosine kinases, including the platelet-derived growth factor receptor. Inhibitors of PtdIns 3-kinase could potentially give a better understanding of the...

Subject

Benzopyran

Phosphatidylinositol

LY294002

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