Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

Zhang, Yongyou; Desai, Amar; Yeun Yang, Sung; Beom Bae, Ki; I. Antczak, Monika; P. Fink, Stephen; Tiwari, Shruti; E. Willis, Joseph; S. Williams, Noelle; M. Dawson, Dawn; Wald, David; Chen, Wei-Dong; Wang, Zhenghe; Kasturi, Lakshmi; A. Larusch, Gretchen; He, Lucy; Cominelli, Fabio; Di Martino, Luca; Djuric, Zora; L. Milne, Ginger; Chance, Mark; Sanabria, Juan; Dealwis, Chris; Mikkola, Debra; Naidoo, Jacinth; Wei, Shuguang; Tai, Hsin-Hsiung; L. Gerson, Stanton; M. Ready, Joseph; Posner, Bruce; K. V. Willson, James; D. Markowitz, Sanford

doi:10.1126/science.aaa2340

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Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

Shared by NobleBlocks on Jun 12, 2015 • 12:00 AM UTC

Authors:

Yongyou Zhang

Amar Desai

Sung Yeun Yang

Abstract

A shot in the arm for damaged tissue Tissue damage can be caused by injury, disease, and even certain medical treatments. There is great interest in identifying drugs that accelerate tissue regeneration and recovery, especially drugs that might benefit multiple organ systems. Zhang et al. describe a...

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