An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex

Christopher Garcia, K.; Degano, Massimo; L. Stanfield, Robyn; Brunmark, Anders; R. Jackson, Michael; A. Peterson, Per; Teyton, Luc; A. Wilson, Ian

doi:10.1126/science.274.5285.209

Public

An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex

Shared by NobleBlocks on Oct 11, 1996 • 12:00 AM UTC

Authors:

K. Christopher Garcia

Massimo Degano

Robyn L. Stanfield

Abstract

The central event in the cellular immune response to invading microorganisms is the specific recognition of foreign peptides bound to major histocompatibility complex (MHC) molecules by the αβ T cell receptor (TCR). The x-ray structure of the complete extracellular fragment of a glycosylated αβ TCR ...

Discussions