Vitamin D receptor initiation codon polymorphism influences genetic susceptibility to type 1 diabetes mellitus in the Japanese population.

Ban, Y; Taniyama, M; Yanagawa, T; Yamada, S; Maruyama, T; Kasuga, A; Ban, Y

doi:10.1186/1471-2350-2-7

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Vitamin D receptor initiation codon polymorphism influences genetic susceptibility to type 1 diabetes mellitus in the Japanese population.

Shared by NobleBlocks on Jan 1, 2001 • 12:00 AM UTC

Authors:

Y Ban

M Taniyama

T Yanagawa

Abstract

BACKGROUND: Vitamin D has been shown to exert manifold immunomodulatory effects. Type 1 diabetes mellitus (T1DM) is regarded to be immune-mediated and vitamin D prevents the development of diabetes in the NOD mouse. We studied the association between T1DM and the initiation codon polymorphism in exo...

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