Voriconazole potentiates warfarin-induced prothrombin time prolongation.

<h4>Aims</h4>Voriconazole is a novel triazole with broad-spectrum antifungal activity. It is likely that some patients receiving voriconazole may also require treatment with the anticoagulant warfarin. Cytochrome P450 isoenzymes are important in the metabolism of both these drugs. This study investi... View More