Antibody-functionalized nanoparticles for imaging cancer: influence of conjugation to gold nanoparticles on the biodistribution of 89Zr-labeled cetuximab in mice.

L, Karmani; D, Labar; V, Valembois; V, Bouchat; PG, Nagaswaran; A, Bol; J, Gillart; P, Levêque; C, Bouzin; D, Bonifazi; C, Michiels; O, Feron; V, Grégoire; S, Lucas; Borght T, Vander; B, Gallez

doi:10.1002/cmmi.1539

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Antibody-functionalized nanoparticles for imaging cancer: influence of conjugation to gold nanoparticles on the biodistribution of 89Zr-labeled cetuximab in mice.

Shared by NobleBlocks on Sep 1, 2013 • 12:00 AM UTC

Authors:

Karmani L

Labar D

Valembois V

Abstract

Antibody-labeled gold nanoparticles represent a promising novel tool regarding cancer imaging and therapy. Nevertheless, the characterization of biodistribution of such immunonanocarriers has been poorly documented. In this study, the biodistribution of (89)Zr-labeled cetuximab before and after the ...

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