Green tea increases the anti‐inflammatory tristetraprolin and decreases the pro‐inflammatory tumor necrosis factor mRNA levels in rats

Cao, Heping; Kelly, Meghan; W. Kari, Frank; Dawson, Harry; Coves, Sara; Marie Roussel, Anne; A. Anderson, Richard

doi:10.1096/fasebj.21.5.a165-d

Public

Green tea increases the anti‐inflammatory tristetraprolin and decreases the pro‐inflammatory tumor necrosis factor mRNA levels in rats

Shared by NobleBlocks on Apr 1, 2007 • 12:00 AM UTC

Authors:

Heping Cao

Meghan Kelly

Frank W. Kari

Abstract

Tristetraprolin (TTP) family proteins have anti‐inflammatory activity by binding to and destabilizing pro‐inflammatory mRNAs such as TNF mRNA, and represent a potential therapeutic target for inflammation‐related diseases. Tea has anti‐inflammatory properties but the molecular mechanism is unknown. ...

Subject

Tristetraprolin

Tumor necrosis factor alpha

Messenger RNA

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