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Обзор данных о механизмах влияния гидратированных фуллеренов на биологические системы

Published in Научные ведомости Белгородского государственного университета. Серия: Естественные науки • Jan 1, 2011
NobleIDNI5P67W57R67S47
Authors:
Т. О. Волкова
,
С В Ширинкин
,
Anton Albertovich Shaposhnikov

Abstract

Imatinib mesylate, licensed to treat chronic myelogenous leukemia and gastrointestinal stromal tumors, is metabolized by means of cytochrome P450 3A and excreted primarily in the bile. Although the bioavailability of imatinib mesylate is more than 97%, the exact gastrointestinal site of its absorpti...

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