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Διπλή διάσπαση βήτα

Published • Nov 7, 2010
Authors:
Ιωάννης Τσινταβής

Abstract

Adverse events relating to insertional mutagenesis have reinforced the interest in self-inactivating (SIN) gamma-retroviral and lentiviral vectors without enhancer-promoter sequences in the U3 region of the long terminal repeats. However, SIN vectors suffer from leaky transcriptional termination, in...

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