NKG2D is a Key Receptor for Recognition of Bladder Cancer Cells by IL-2-Activated NK Cells and BCG Promotes NK Cell Activation.

EM, García-Cuesta; S, López-Cobo; M, Álvarez-Maestro; G, Esteso; G, Romera-Cárdenas; M, Rey; RL, Cassady-Cain; A, Linares; A, Valés-Gómez; HT, Reyburn; L, Martínez-Piñeiro; M, Valés-Gómez

doi:10.3389/fimmu.2015.00284

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NKG2D is a Key Receptor for Recognition of Bladder Cancer Cells by IL-2-Activated NK Cells and BCG Promotes NK Cell Activation.

Shared by NobleBlocks on Jun 8, 2015 • 12:00 AM UTC

Authors:

García-Cuesta EM

López-Cobo S

Álvarez-Maestro M

Abstract

Intravesical instillation of bacillus Calmette-Guérin (BCG) is used to treat superficial bladder cancer, either papillary tumors (after transurethral resection) or high-grade flat carcinomas (carcinoma in situ), reducing recurrence in about 70% of patients. Initially, BCG was proposed to work throug...

Subject

Bladder cancer

Natural killer cells

Mycobacterium bovis

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