Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study.

J, Kuhle; G, Disanto; R, Dobson; R, Adiutori; L, Bianchi; J, Topping; JP, Bestwick; UC, Meier; M, Marta; Costa G, Dalla; T, Runia; E, Evdoshenko; N, Lazareva; E, Thouvenot; P, Iaffaldano; V, Direnzo; M, Khademi; F, Piehl; M, Comabella; M, Sombekke; J, Killestein; H, Hegen; S, Rauch; S, D'Alfonso; JC, Alvarez-Cermeño; P, Kleinová; D, Horáková; R, Roesler; F, Lauda; S, Llufriu; T, Avsar; U, Uygunoglu; A, Altintas; S, Saip; T, Menge; C, Rajda; R, Bergamaschi; N, Moll; M, Khalil; R, Marignier; I, Dujmovic; H, Larsson; C, Malmestrom; E, Scarpini; C, Fenoglio; S, Wergeland; A, Laroni; V, Annibali; S, Romano; AD, Martínez; A, Carra; M, Salvetti; A, Uccelli; Ø, Torkildsen; KM, Myhr; D, Galimberti; K, Rejdak; J, Lycke; JL, Frederiksen; J, Drulovic; C, Confavreux; D, Brassat; C, Enzinger; S, Fuchs; I, Bosca; J, Pelletier; C, Picard; E, Colombo; D, Franciotta; T, Derfuss; R, Lindberg; Ö, Yaldizli; L, Vécsei; BC, Kieseier; HP, Hartung; P, Villoslada; A, Siva; A, Saiz; H, Tumani; E, Havrdová; LM, Villar; M, Leone; N, Barizzone; F, Deisenhammer; C, Teunissen; X, Montalban; M, Tintoré; T, Olsson; M, Trojano; S, Lehmann; G, Castelnovo; S, Lapin; R, Hintzen; L, Kappos; R, Furlan; V, Martinelli; G, Comi; SV, Ramagopalan; G, Giovannoni

doi:10.1177/1352458514568827

Public

Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study.

Shared by NobleBlocks on Feb 13, 2015 • 12:00 AM UTC

Authors:

Kuhle J

Disanto G

Dobson R

Abstract

<h4>Background and objective</h4>We explored which clinical and biochemical variables predict conversion from clinically isolated syndrome (CIS) to clinically definite multiple sclerosis (CDMS) in a large international cohort.<h4>Methods</h4>Thirty-three centres provided serum samples from 1047 CIS ...

Subject

Clinically Isolated Syndrome (Cis)

Oligoclonal Bands (Ocbs)

Clinically Definite Multiple Sclerosis (Cdms)

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