Прикладная химия Джабира ибн Хайяна и ее роль в естествознании
Published in Башкирский химический журнал • Jan 1, 2011
Authors:
М. Ф. Каримов
Abstract
Comparative molecular field analysis (CoMFA) was performed on twenty-three pyrimethamine (pyr) derivatives active against quadruple mutant type (Asn51Ile, Cys59Arg, Ser108Asn, Ile164Leu) dihydrofolate reductase of Plasmodium falcipaarum (PfDHFR). The represented CoMFA models were evaluated based on ...
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