Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

R. Mosmann, Timothy; Cherwinski, Holly; W Bond, M; Giedlin, Martin; L. Coffman, Robert

doi:10.4049/jimmunol.136.7.2348

Public

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

Shared by NobleBlocks on Apr 1, 1986 • 12:00 AM UTC

Authors:

Timothy R. Mosmann

Holly Cherwinski

M W Bond

Abstract

A panel of antigen-specific mouse helper T cell clones was characterized according to patterns of lymphokine activity production, and two types of T cell were distinguished. Type 1 T helper cells (TH1) produced IL 2, interferon-gamma, GM-CSF, and IL 3 in response to antigen + presenting cells or to ...

Subject

Lymphokine

Biology

T cell

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