Dapagliflozin, metformin XR, or both: initial pharmacotherapy for type 2 diabetes, a randomised controlled trial.

RR, Henry; AV, Murray; MH, Marmolejo; D, Hennicken; A, Ptaszynska; JF, List

doi:10.1111/j.1742-1241.2012.02911.x

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Dapagliflozin, metformin XR, or both: initial pharmacotherapy for type 2 diabetes, a randomised controlled trial.

Shared by NobleBlocks on Mar 13, 2012 • 12:00 AM UTC

Authors:

Henry RR

Murray AV

Marmolejo MH

Abstract

<h4>Background</h4>Combining metformin (XR) with dapagliflozin to initiate pharmacotherapy in patients with type 2 diabetes (T2D) and high baseline HbA1c may be advantageous. We conducted two randomised, double-blind, three-arm 24-week trials in treatment-naïve patients to compare dapagliflozin plus...

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