Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona: a comprehensive quantitative proteomic analysis.

S, Tenzer; D, Docter; S, Rosfa; A, Wlodarski; J, Kuharev; A, Rekik; SK, Knauer; C, Bantz; T, Nawroth; C, Bier; J, Sirirattanapan; W, Mann; L, Treuel; R, Zellner; M, Maskos; H, Schild; RH, Stauber

doi:10.1021/nn201950e

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Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona: a comprehensive quantitative proteomic analysis.

Shared by NobleBlocks on Aug 25, 2011 • 12:00 AM UTC

Authors:

Tenzer S

Docter D

Rosfa S

Abstract

In biological fluids, proteins associate with nanoparticles, leading to a protein "corona" defining the biological identity of the particle. However, a comprehensive knowledge of particle-guided protein fingerprints and their dependence on nanomaterial properties is incomplete. We studied the long-l...

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