FAK overexpression is correlated with tumour invasiveness and lymph node metastasis in oesophageal squamous cell carcinoma.

T, Miyazaki; H, Kato; M, Nakajima; M, Sohda; Y, Fukai; N, Masuda; R, Manda; M, Fukuchi; K, Tsukada; H, Kuwano

doi:10.1038/sj.bjc.6601050

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FAK overexpression is correlated with tumour invasiveness and lymph node metastasis in oesophageal squamous cell carcinoma.

Published in British journal of cancer • Jul 1, 2003

Authors:

Miyazaki T

Kato H

Nakajima M

Abstract

Focal adhesion kinase (p125(FAK); 'FAK') is a tyrosine kinase that is localised to cellular focal adhesions and is associated with a number of other proteins, such as integrin adhesion receptors. We performed an immunohistochemical analysis of FAK protein expression to determine the relationship bet...

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