Intraepithelial CD8+ T-cell-count becomes a prognostic factor after a longer follow-up period in human colorectal carcinoma: possible association with suppression of micrometastasis

Chiba, Takashi; Ohtani, Haruo; Mizoi, Takayuki; Naito, Yoshitaka; Sato, Eriko; Nagura, H; Ohuchi, A; Ohuchi, Kazuo; Shiiba, Kenichi; Kurokawa, Yukinori; Satomi, S.

doi:10.1038/sj.bjc.6602201

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Intraepithelial CD8+ T-cell-count becomes a prognostic factor after a longer follow-up period in human colorectal carcinoma: possible association with suppression of micrometastasis

Published in British Journal of Cancer • Oct 19, 2004

Authors:

Takashi Chiba

Haruo Ohtani

Takayuki Mizoi

Abstract

T-cell infiltration into human cancer tissues can be a manifestation of host immune responses to cancer cells. The present study was undertaken to explore the clinicopathological significance of intraepithelial CD8(+) T cells using 371 consecutively sampled human colorectal carcinomas. By univariate...

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Open Access

Subject

Micrometastasis

Medicine

CD8

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