Saccharomyces cerevisiae- and Candida albicans-derived mannan induced production of tumor necrosis factor alpha by human monocytes in a CD14- and Toll-like receptor 4-dependent manner.

H, Tada; E, Nemoto; H, Shimauchi; T, Watanabe; T, Mikami; T, Matsumoto; N, Ohno; H, Tamura; K, Shibata; S, Akashi; K, Miyake; S, Sugawara; H, Takada

doi:10.1111/j.1348-0421.2002.tb02727.x

Public

Saccharomyces cerevisiae- and Candida albicans-derived mannan induced production of tumor necrosis factor alpha by human monocytes in a CD14- and Toll-like receptor 4-dependent manner.

Shared by NobleBlocks on Jan 1, 2002 • 12:00 AM UTC

Authors:

Tada H

Nemoto E

Shimauchi H

Abstract

The cytokine-inducing activities of fungal polysaccharides were examined in human monocytes in culture, with special reference to CD14 and Toll-like receptors (TLRs). Tumor necrosis factor alpha (TNF-alpha) production by monocytes was markedly induced in a dose-dependent manner upon stimulation with...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!