Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.

X, Hu; E, Pickering; YC, Liu; S, Hall; H, Fournier; E, Katz; B, Dechairo; S, John; Eerdewegh P, Van; H, Soares

doi:10.1371/journal.pone.0016616

Public

Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.

Shared by NobleBlocks on Feb 24, 2011 • 12:00 AM UTC

Authors:

Hu X

Pickering E

Liu YC

Abstract

Recent GWAS studies focused on uncovering novel genetic loci related to AD have revealed associations with variants near CLU, CR1, PICALM and BIN1. In this study, we conducted a genome-wide association study in an independent set of 1034 cases and 1186 controls using the Illumina genotyping platform...

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