Regulation of CARD8 Expression by ANRIL and Association of CARD8 SNP rs2043211 (p.C10X) with Ischemic Stroke

Bai, Ying; Nie, Shaofang; Jiang, Guiqing; Zhou, Yingchao; Zhou, Mengchen; Zhao, Yuanyuan; Li, Sisi; Wang, Fan; Lu, Qiulun; Huang, Yufeng; Yang, Qin; Li, Qingxian; Li, Yue; Xia, Yunlong; Liu, Y.; Liu, Jinqiu; Qian, J.; Li, Bin; Wu, Gang; Wu, Yanxia; Wang, Binbin; Cheng, Xiang; Yang, Yanzong; Ke, Tie; Li, Hui; Ren, X.; Ma, Xu; Liao, Yuhua; Xu, Chengqi; Tu, X.; Wang, Q.

doi:10.1161/STROKEAHA.113.003393

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Regulation of CARD8 Expression by ANRIL and Association of CARD8 SNP rs2043211 (p.C10X) with Ischemic Stroke

Shared by NobleBlocks on Jan 2, 2014 • 12:00 AM UTC

Authors:

Ying Bai

Shaofang Nie

Guiqing Jiang

Abstract

Background and Purpose— ANRIL has long been considered as the strongest candidate gene at the 9p21 locus, robustly associated with stroke and coronary artery disease. However, the underlying molecular mechanism remains unknown. The present study works to elucidate such a mechanism. Methods— Using ex...

Subject

Medicine

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