Plasminogen Activator Inhibitor Type-1 Synthesis and mRNA Expression in HepG2 Cells Are Regulated by VLDL

Sironi, Luigi; Mussoni, L.; Prati, L.; Baldassarre, Damiano; Camera, Marina; Banfi, Cristina; Tremoli, Elena

doi:10.1161/01.atv.16.1.89

Public

Plasminogen Activator Inhibitor Type-1 Synthesis and mRNA Expression in HepG2 Cells Are Regulated by VLDL

Shared by NobleBlocks on Jan 1, 1996 • 12:00 AM UTC

Authors:

Luigi Sironi

L. Mussoni

L. Prati

Abstract

The effect of VLDL on plasminogen activator inhibitor type 1 biosynthesis in HepG2 cells was investigated. Exposure of HepG2 cells to VLDL (range, 10 to 100 micrograms protein per milliliter) for 16 hours resulted in an enhanced release of PAI-1 antigen and PAI activity into conditioned medium, acco...

Subject

Plasminogen activator

Messenger RNA

Chemistry

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