Emmprin (basigin/CD147): matrix metalloproteinase modulator and multifunctional cell recognition molecule that plays a critical role in cancer progression.

K, Nabeshima; H, Iwasaki; K, Koga; H, Hojo; J, Suzumiya; M, Kikuchi

doi:10.1111/j.1440-1827.2006.01972.x

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Emmprin (basigin/CD147): matrix metalloproteinase modulator and multifunctional cell recognition molecule that plays a critical role in cancer progression.

Shared by NobleBlocks on Jul 1, 2006 • 12:00 AM UTC

Authors:

Nabeshima K

Iwasaki H

Koga K

Abstract

Emmprin (basigin, CD147) is a cell surface glycoprotein that belongs to the immunoglobulin superfamily. It is highly expressed on the surface of tumor cells and stimulates adjacent fibroblasts or tumor cells to produce matrix metalloproteinases. Moreover, it has recently been shown that emmprin also...

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