Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing.

W Kunstman, John; Christofer Juhlin, C; Goh, Gerald; C Brown, Taylor; Stenman, Adam; M Healy, James; C Rubinstein, Jill; Choi, Murim; Kiss, Nimrod; Nelson-Williams, Carol; Mane, Shrikant; L Rimm, David; L Prasad, Manju; Höög, Anders; Zedenius, Jan; Larsson, Catharina; Korah, Reju; P Lifton, Richard; Carling, Tobias

doi:10.1093/hmg/ddu749

Public

Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing.

Shared by NobleBlocks on Apr 15, 2015 • 12:00 AM UTC

Authors:

John W Kunstman

C Christofer Juhlin

Gerald Goh

Abstract

Anaplastic thyroid carcinoma (ATC) is a frequently lethal malignancy that is often unresponsive to available therapeutic strategies. The tumorigenesis of ATC and its relationship to the widely prevalent well-differentiated thyroid carcinomas are unclear. We have analyzed 22 cases of ATC as well as 4...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!