Adenosine A(2A) receptors measured with [C]TMSX PET in the striata of Parkinson's disease patients.

Mishina, Masahiro; Ishiwata, Kiichi; Naganawa, Mika; Kimura, Yuichi; Kitamura, Shin; Suzuki, Masahiko; Hashimoto, Masaya; Ishibashi, Kenji; Oda, Keiichi; Sakata, Muneyuki; Hamamoto, Makoto; Kobayashi, Shiro; Katayama, Yasuo; Ishii, Kenji

doi:10.1371/journal.pone.0017338

Public

Adenosine A(2A) receptors measured with [C]TMSX PET in the striata of Parkinson's disease patients.

Shared by NobleBlocks on Feb 28, 2011 • 12:00 AM UTC

Authors:

Masahiro Mishina

Kiichi Ishiwata

Mika Naganawa

Abstract

Adenosine A(2A) receptors (A2ARs) are thought to interact negatively with the dopamine D(2) receptor (D2R), so selective A2AR antagonists have attracted attention as novel treatments for Parkinson's disease (PD). However, no information about the receptor in living patients with PD is available. The...

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