Inhibition of ischemia/reperfusion injury and chronic graft deterioration by a single-donor treatment with cobalt-protoporphyrin for the induction of heme oxygenase-1.

SG, Tullius; M, Nieminen-Kelhä; R, Buelow; A, Reutzel-Selke; PN, Martins; J, Pratschke; U, Bachmann; M, Lehmann; D, Southard; S, Iyer; G, Schmidbauer; B, Sawitzki; P, Reinke; P, Neuhaus; HD, Volk

doi:10.1097/00007890-200209150-00001

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Inhibition of ischemia/reperfusion injury and chronic graft deterioration by a single-donor treatment with cobalt-protoporphyrin for the induction of heme oxygenase-1.

Shared by NobleBlocks on Sep 1, 2002 • 12:00 AM UTC

Authors:

Tullius SG

Nieminen-Kelhä M

Buelow R

Abstract

Today, the major problem in organ transplantation is not acute graft rejection but chronic graft deterioration. In addition to alloantigen-specific events, alloantigen independent factors like donor age, previous diseases, consequences of brain death, and perioperative events of ischemia/reperfusion...

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