Serum levels of galactose-deficient immunoglobulin (Ig) A1 and related immune complex are associated with disease activity of IgA nephropathy.

Suzuki, Yusuke; Matsuzaki, Keiichi; Suzuki, Hitoshi; Okazaki, Keiko; Yanagawa, Hiroyuki; Ieiri, Norio; Sato, Mitsuhiro; Sato, Toshinobu; Taguma, Yoshio; Matsuoka, Joe; Horikoshi, Satoshi; Novak, Jan; Hotta, Osamu; Tomino, Yasuhiko

doi:10.1007/s10157-013-0921-6

Public

Serum levels of galactose-deficient immunoglobulin (Ig) A1 and related immune complex are associated with disease activity of IgA nephropathy.

Shared by NobleBlocks on Oct 1, 2014 • 12:00 AM UTC

Authors:

Yusuke Suzuki

Keiichi Matsuzaki

Hitoshi Suzuki

Abstract

BACKGROUND: The primary abnormal manifestation in immunoglobulin A nephropathy (IgAN) is recurring bouts of hematuria with or without proteinuria. Although immunohistochemical analysis of renal biopsy tissue remains the gold standard not only for diagnosis but also for evaluating the activity of IgA...

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