Association of B2 receptor polymorphisms and ACE activity with ACE inhibitor-induced angioedema in black and mixed-race South Africans.

RR, Moholisa; BR, Rayner; Owen E, Patricia; SL, Schwager; JS, Stark; M, Badri; CL, Cupido; ED, Sturrock

doi:10.1111/jch.12104

Public

Association of B2 receptor polymorphisms and ACE activity with ACE inhibitor-induced angioedema in black and mixed-race South Africans.

Shared by NobleBlocks on Apr 11, 2013 • 12:00 AM UTC

Authors:

Moholisa RR

Rayner BR

Patricia Owen E

Abstract

Angiotensin-converting enzyme (ACE) inhibitors are first-line therapy for the treatment of hypertension, congestive heart failure, and diabetic nephropathy. ACE inhibitors are associated with adverse side effects such as persistent dry cough (ACE-cough) and, rarely, life-threatening angioedema (ACE-...

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