Prolongation of allogeneic heart graft survival in rats by administration of a peptide (a.a. 75-84) from the alpha 1 helix of the first domain of HLA-B7 01.

MC, Cuturi; R, Josien; P, Douillard; C, Pannetier; D, Cantarovich; H, Smit; S, Ménoret; P, Pouletty; C, Clayberger; JP, Soulillou

doi:10.1097/00007890-199503150-00003

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Prolongation of allogeneic heart graft survival in rats by administration of a peptide (a.a. 75-84) from the alpha 1 helix of the first domain of HLA-B7 01.

Shared by NobleBlocks on Mar 1, 1995 • 12:00 AM UTC

Authors:

Cuturi MC

Josien R

Douillard P

Abstract

Allospecific T lymphocytes mediate graft rejection through specific, direct or indirect, recognition of processed determinants of foreign MHC class I molecules. Small synthetic peptides derived from highly conserved sequences of the alpha 1 helix of the first domain of certain MHC class I molecules ...

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