Delayed cerebral ischemia and spreading depolarization in absence of angiographic vasospasm after subarachnoid hemorrhage.

J, Woitzik; JP, Dreier; N, Hecht; I, Fiss; N, Sandow; S, Major; M, Winkler; YA, Dahlem; J, Manville; M, Diepers; E, Muench; H, Kasuya; P, Schmiedek; P, Vajkoczy

doi:10.1038/jcbfm.2011.169

Public

Delayed cerebral ischemia and spreading depolarization in absence of angiographic vasospasm after subarachnoid hemorrhage.

Shared by NobleBlocks on Dec 7, 2011 • 12:00 AM UTC

Authors:

Woitzik J

Dreier JP

Hecht N

Abstract

It has been hypothesized that vasospasm is the prime mechanism of delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH). Recently, it was found that clusters of spreading depolarizations (SDs) are associated with DCI. Surgical placement of nicardipine prolonged-release impl...

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