Autoantibodies activating human beta1-adrenergic receptors are associated with reduced cardiac function in chronic heart failure.

Background Autoantibodies against synthetic peptides of beta-adrenergic receptors have been observed in human cardiomyopathy. However, it has never been shown that such antibodies really interact with native human beta-adrenergic receptors, nor has the clinical impact of such an interaction been inv... View More